Protein Analysis Reagents
MilliporeSigma™ Calbiochem™ ETV1 Inhibitor, BRD32048
Cell-permeable, reversibly binds to ETV1 (KD = 17.1 μM) and reduces its transcriptional activity, independent of its binding to DNA.
MilliporeSigma™ Calbiochem™ Camptothecin, Camptotheca acuminata
A cell-permeable DNA topoisomerase I inhibitor.
MilliporeSigma™ Calbiochem™ Cathepsin B Substrate III, Fluorogenic
Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.
MilliporeSigma™ Calbiochem™ Cathepsin Inhibitor I
The Cathepsin Inhibitor I controls the biological activity of Cathepsin. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ (±)-Blebbistatin
(±)-Blebbistatin, CAS 674289-55-5, is a cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis in vertebrate cells.
MilliporeSigma™ Calbiochem™ Dkk Inhibitor II, IIIC3a
An enhanced in solution stable gallocyanine analog that directly and reversibly targets human LRP5/6 (low density lipoprotein-related protein 5/6), and disrupts its interaction with Dkk (Dickkopf) in a competitive manner
MilliporeSigma™ Calbiochem™ Syk Inhibitor IV, BAY 61-3606
The Syk Inhibitor IV, BAY 61-3606, also referenced under CAS 732938-37-8, controls the biological activity of Syk.
MilliporeSigma™ Calbiochem™ CTOP
A potent antagonist highly selective forμ opioid receptor (Ki
MilliporeSigma™ Calbiochem™ Diaphanous (mDia)-related Formin Agonist, IMM01
An agonist of mammalian Diaphanous (mDia)-related formins that disrupts diaphanous inhibitory domain (DID) and diaphanous autoregulatory domain (DAD) interaction (IC50 = 140 nM).
MilliporeSigma™ Calbiochem™ Collagenase Inhibitor I
The Collagenase Inhibitor I controls the biological activity of Collagenase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Adenosine Receptor Agonist, NECA
A cell-permeable adenosine analog that acts a potent non-selective agonist of adenosine receptors (Ki = 14 nM, 20 nM
MilliporeSigma™ Calbiochem™ Focal Adhesion Kinase Inhibitor III
A cell-permeable pyrazolobenzothiazinedioxide compound that targets and locks FAK in its inactive conformation, resulting in preincubation time-dependent inhibition in kinase assays and FAK autophosphorylation in human prostate cancer PC3M-luc cells (IC50
MilliporeSigma™ Calbiochem™ GPR40 Agonist III
A cell-permeable, highly potent, and selective agonist of free fatty acid receptor 1 (FFA1; GPR40; EC50 = 20 nM in FFA1-transfected HEK-293 cells).
MilliporeSigma™ Calbiochem™ PRMT Inhibitor VII, DB867
A cell-permeable, selective inhibitor of protein arginine methyltransferase 1 (PRMT1; IC50 = 9.5 μM).
MilliporeSigma™ Calbiochem™ Foxo1 Inhibitor, AS1842856
Foxo1 Inhibitor, AS1842856, is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 (IC50 = 33 nM). Directly binds to the active Foxo1, but not the Ser256-phosphorylated form.